DNA replication

DNA replication regulation is one of the core events of cell cycle regulation.

DNA复制调控是细胞周期调控的一个核心事件。

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Regulation of DNA Replication and Human Major Diseases& A Direction for Mid-Long Strategy Development of Biomedical Science in China

DNA复制调控与人类重大疾病&我国生物医学科学中长期战略发展的一个方向

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The cell model was useful for evaluating potential genetic engineering vaccine and for studying on HBV DNA replication.

该细胞模型的初步建立有利于筛选高效价的基因工程疫苗和进行HBV复制行为的研究。

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Regulation of DNA Replication Initiation in Eukaryotes

真核生物DNA复制起始调控

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Regulation of Initiation of DNA Replication in Budding Yeast

芽殖酵母DNA复制起始调控

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The target of anti-tumor effect of inhibition of topoisomerase I, to prevent tumor cell DNA replication.

其抗肿瘤作用靶点是抑制拓扑异构酶Ⅰ，阻止肿瘤细胞DNA的复制。

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Modifications of DNA by endogenous or environmental reactive species could lead to mutation during DNA replication, which is the initiation step of carcinogenesis.

去氧核醣核酸（DNA）被体内或环境中具反应性物种修饰后会在DNA复制时导致基因突变，为细胞癌化的第一步。

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Inhibitory Effect of Berberine on Epstein-barr DNA Replication

小檗碱对Epstein-Barr病毒DNA复制的抑制作用

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Thus, oxidative DNA damage adversely affects transcription and DNA replication in melanocytes.

这样氧化损伤的DNA负性影响黑色素细胞的转录和DNA复制.

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RPA plays central roles in the processes of DNA replication and repair.

RPA在DNA复制和修复过程中起着重要的作用。

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Genes encoding enzymes involved in DNA replication are potential targets for mutations leading to cancer. Identification of Genetic Variants in Base Excision Repair Pathway and Their Associations with Risk of Esophageal Squamous Cell Carcinoma

碱基切除修复（BER），是清除细胞内DNA损伤的主要途径。碱基切除修复基因SNP的鉴定及其与食管癌的关联研究

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The 5 ′-end Gap Repair after Linear DNA Replication

线性DNA复制后5′端空缺的填补

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Proliferating cell nuclear antigen ( PCNA) is a growth-regulated protein which coordinates events in DNA replication, DNA repair, cell cycle control and epigenetic inheritance. PCNA gene is regulated at both transcriptional and post-transcriptional levels.

增殖细胞核抗原（proliferating cell nuclear antigen，PCNA，PCNA）是一种生长调控蛋白，在DNA复制、修复、细胞周期调控、基因外遗传（epigenetic inheritance）等事件的协同机制中发挥重要功能。

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Study of the DNA Replication Pattern of an Unbalanced Translocation Chromosome in Leukocyte Cultures

X-X染色体不平衡易位及DNA复制类型的研究

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Fluoroquinolones, primarily by inhibiting bacterial DNA gyrase, so that bacteria can not engage in normal DNA replication and division, resulting in rapid bactericidal effect.

氟喹诺酮类药物主要通过抑制细菌的DNA旋转酶，使细菌不能进行正常DNA复制和分裂，从而产生快速杀菌作用。

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in order to maintain the stability of heredity and the accuracy of dna replication, there is an integrated dna repair system, which can repair dna damage or mutation in either bacteria or human.

为维持遗传的稳定，保持DNA复制的真实性，无论是细菌还是人类都有着一套完整的DNA修复系统，修复受损或突变的DNA。

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Research Progress of Structure and Function on Eukaryotic Origins of DNA Replication

真核DNA复制起始点的结构与功能研究进展

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Checkpoints respond to DNA damage and DNA replication block by arresting the cell cycle to provide time for repair and by inducing transcription of genes that facilitate repair. Until the damage was repaired, the cell processed into division cycle.

正常细胞发生DNA损伤或是合成阻断时，将通过细胞周期检查点阻滞在特定的细胞周期内，并诱导某些特殊的转录反应，直到损伤修复后才恢复正常分裂。

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These results would contribute to the insight into the DNA replication mechanism regulated by cell cycle.

这些结果有助于理解细胞周期进程中DNA复制的调控机理。

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A Novel Model for DNA Replication and Transcription

一种新的DNA复制和转录模型

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The adducts disturb the structure of DNA and inhibit DNA replication.

加合物的形成扰乱了DNA模板的结构，抑制了DNA复制。

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Generally, Quinolones disturb bacterial DNA replication by binding topoisomerase type ⅱ.

一般认为，喹诺酮类抗菌药通过结合细菌Ⅱ类拓扑异构酶，干扰细菌复制，而发挥抑菌作用。

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The Association of Vaccinia Virus DNA Replication with the Intermediate Filament

痘苗病毒的DNA复制中间纤维的关系

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Further study demonstrated that the antibacterial mechanism of rosmarinic acid was associated with the effects of rosmarinic acid on the permeability of cell membrane, protein metabolism and DNA replication.

迷迭香酸可改变细菌细胞膜的通透性，导致还原糖和蛋白质的渗漏而影响细胞代谢，通过抑制DNA聚合酶的活性而影响DNA复制，从而发挥了抑菌作用。

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The fidelity of DNA replication in prokaryotes is discussed in this paper.

本文概述了促成原核生物DNA复制准确性的因素。

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DNA replication, repairing and recombination must depend on the interaction with the protein.

DNA的复制、修复与重组，必须依赖与蛋白质的相互作用。

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Both DNA and RNA can act as genetic materials. The molecular mechanism of DNA replication has been lucidly illuminated, however, the RNA replication has not been fully understood.

DNA和RNA都是遗传物质，人们对于DNA的复制机制已经有了比较透彻的了解，但对RNA的复制还不清楚。

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Mitochondrial DNA Replication and Its Regulation

线粒体DNA复制及其调控

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Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.

目的筛选与苯中毒有关的DNA复制及损伤修复基因。

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The Relationship Between Nuclear DNA Replication and Seed Quality

细胞核DNA复制与种子质量的关系

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